As covered in our 10 Things No One Tells You About Machining article, runout is everywhere! However with most tools we use this amount is negligible. Using, say, a 3/8” endmill with .0008” of TIR won’t have significant consequences (especially when roughing). Unless you’re chasing tenths, the runout is such a small percentage of the tool’s overall diameter (~0.21%) that it wont have any noticeable affects. As you small diameter tools, this percentage begins to increase. Using a 1/32” endmill with the same runout amounts to a TIR that is 2.56% (about a 10x increase!). This can result in uneven wear, chatter, bad surface finish, missing tolerances, and even broken tools.